As a guy asking girls out, it’s not so much whether they’d like being asked out as a concern, as to whether they’d be actively bothered, made uncomfortable, or creeped out. A lot of women don’t feel safe in expressing, at least directly, when they don’t like being asked out or otherwise aren’t interested, particularly when it’s a guy asking them out who they don’t already really know, for understandable reasons.
If it was less common for women to be made uncomfortable and feel unsafe saying that they simply aren’t interested when men shoot their shot, it’d be different, but I and a lot of other men are hesitant to shoot our shot, not simply because she might not like it, but because we don’t want to risk creeping her out or making her uncomfortable in doing so, especially if we might not notice or realize it right away because she doesn’t feel safe in communicating how she feels.